EccDNA formation is dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA double-strand break
Selected by
05 January 2021
Sree Rama Chaitanya
Single cell sequencing of the small and AT-skewed genome of malaria parasites
Selected by
10 December 2020
Mariana De Niz
ARID1A regulates R-loop associated DNA replication stress
Selected by
05 December 2020
Sree Rama Chaitanya
Antifungal effects of PC945, a novel inhaled triazole, on Candida albicans-infected immunocompromised mice
Selected by
23 September 2020
Zhang-He Goh
Pharmacological Insights into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure
Selected by
08 September 2020
Zhang-He Goh
Small molecules exploiting structural differences within microRNA-200 precursors family members reverse a type 2 diabetes phenotype
Selected by
25 August 2020
Zhang-He Goh
Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity
AND
Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity
Selected by
07 August 2020
Zhang-He Goh
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
AND
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Selected by
31 July 2020
Yen-Chung Chen
Electron Transfer from Cytochrome P450 Reductase to Cytochrome P450: Towards a Structural and Dynamic Understanding
Selected by
27 July 2020
Zhang-He Goh
Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
AND
Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
Selected by
25 July 2020
Zhang-He Goh, Josie Gibson
Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism
Selected by
18 June 2020
Zhang-He Goh
Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses
Selected by
23 May 2020
Zhang-He Goh